Keluwih: Jurnal Kesehatan dan Kedokteran https://journal.ubaya.ac.id/index.php/kesdok <p style="text-align: justify;"><strong>Keluwih: Jurnal Kesehatan dan Kedokteran</strong> is an online, open access, and peer-reviewed journal. JKK publishes two issues per year: in December (covering December-May) and in June (covering June-November) First published in December 2019. This journal aims to disseminate the results of original research, case report, and critical reviews in the fields of health and medicine. This focus and scopes include, but are not limited to a pharmacy, medicine, public health, and health biotechnology fields.</p> <p style="text-align: justify;"><br><strong>eISSN:&nbsp;</strong>2715-6419</p> Direktorat Penerbitan dan Publikasi Ilmiah, Universitas Surabaya en-US Keluwih: Jurnal Kesehatan dan Kedokteran 2715-6419 <ul> <li class="show">Articles published in Keluwih: JKK are licensed under a <a title="CC BY SA" href="https://creativecommons.org/licenses/by-sa/4.0/">Creative Commons Attribution-ShareAlike 4.0 International</a> license. You are free to copy, transform, or redistribute articles for any lawful purpose in any medium, provided you give appropriate credit to the original author(s) and the journal, link to the license, indicate if changes were made, and redistribute any derivative work under the same license.</li> <li class="show">Copyright on articles is retained by the respective author(s), without restrictions. A non-exclusive license is granted to Kluwih: JKK to publish the article and identify itself as its original publisher, along with the commercial right to include the article in a hardcopy issue for sale to libraries and individuals.</li> <li class="show">By publishing in Keluwih: JKK, authors grant any third party the right to use their article to the extent provided by the <a title="CC BY SA" href="https://creativecommons.org/licenses/by-sa/4.0/">Creative Commons Attribution-ShareAlike 4.0 International</a> license.</li> </ul> Pengobatan Pasien Gangguan Jiwa yang Dipasung Oleh Keluarga: Studi Kasus di Kabupaten Trenggalek https://journal.ubaya.ac.id/index.php/kesdok/article/view/6050 <p style="text-align: justify;"><strong><em>Abstract</em></strong>—<em>In Trenggalek Regency, East Java Province, psychotic patients are still found on pasung by their families even though the Free Pasung Program has been intensively carried out since 2015 by The Indonesian Government. This research aims to identifying the characteristics and status of pasung, medication history, and patient’s adherence to medication. The data collection was carried out through interviews with family members of patients with pasung and observation of medical records. A total of 14 psychotic patients were included in this study. Patients were in the productive age of 30-60 years (100%), not working (92.86%), the ratio of patients on pasung and with history of pasung was 1:1, the highest educational level was elementary school (71.43%), and family history (14.29%). Out of 14 patients, 3 patients received no medications, 4 patients received both oral and injectable medications, and 7 patients received oral medications; the majority of patients were given complementary medications (64.29%). The most common injections given were haloperidol decanoate and long-acting flufenazine decanoate; while oral medications frequently given were risperidone, chlorpromazine, trihexiphenidyl, haloperidol and trifluoperazine. Patients’ medication adherence rate was 63,64%. This finding indicated the importance of pharmacists’ role in providing drug information and counseling services to improve medication adherence of patients with psychotics.</em></p> <p style="text-align: justify;"><strong><em>Keyword</em><em>s:</em></strong><em> adherence, pasung, pharmacist, psychotic&nbsp; </em></p> <p style="text-align: justify;">&nbsp;</p> <p style="text-align: justify;"><strong>Abstra</strong><strong>k</strong>—Di Kabupaten Trenggalek Provinsi Jawa Timur masih ditemukan pasien gangguan jiwa psikotik yang dipasung oleh keluarga meskipun Program Bebas Pasung sudah gencar dilakukan sejak tahun 2015 oleh pemerintah Indonesia. Penelitian ini bertujuan untuk mengidentifikasi karakteristik dan status pasung, riwayat pengobatan, serta kepatuhan pasien terhadap pengobatan. Metode pengumpulan data melalui wawancara anggota keluarga pasien dengan pasung dan pengamatan rekam medis. Empat belas pasien gangguan jiwa psikotik terlibat dalam penelitian ini. Pasien berusia produktif 30-60 tahun (100%), tidak bekerja (92,86%), rasio status pasien dalam pasung dan riwayat pasung adalah 1:1, riwayat pendidikan terbanyak adalah sekolah dasar (71,43%), dan riwayat keluarga (14,29%). Dari 14 pasien, 3 pasien tidak menerima pengobatan, 4 pasien menerima pengobatan oral dan suntikan, dan 7 pasien menerima pengobatan oral; mayoritas pasien menerima pengobatan komplementer (64,29%). Obat suntikan yang paling umum diberikan adalah haloperidol dekanoat dan flufenazine dekanoat kerja panjang; sedangkan obat oral yang sering diberikan adalah risperidon, klorpromazin, triheksifenidil, haloperidol dan trifluoperazin. Tingkat kepatuhan pengobatan pasien adalah 63,64%. Temuan ini menunjukkan pentingnya peran apoteker dalam memberikan informasi obat dan layanan konseling untuk meningkatkan kepatuhan pengobatan pasien gangguan jiwa psikotik.</p> <p style="text-align: justify;"><strong>Kata kunci:</strong> <em>apoteker, kepatuhan, pasung, psikotik</em></p> Sulisetiorini Adji Prayitno Yosi Irawati Wibowo Copyright (c) 2024 Sulisetiorini, Adji Prayitno, Yosi Irawati Wibowo (Author) http://creativecommons.org/licenses/by-sa/4.0 2024-03-13 2024-03-13 5 2 54 68 Tingkat Pengetahuan dan Stres Ibu Hamil pada Saat Pandemi Covid-19 https://journal.ubaya.ac.id/index.php/kesdok/article/view/5806 <p style="text-align: justify;"><strong><em>Abstract</em></strong>—<em>The COVID-19 pandemic has had several negative impacts on pregnant women, including increased stress levels.This study aims to determine the level of knowledge and stress levels in pregnant women during the pandemic, as well as analyze the relationship between the two. This is a quantitative research study that utilized an analytical observational method and </em><em>a </em><em>cross-sectional study design. The sampling technique employed was purposive sampling. Data was collected through the distribution of questionnaires containing statements about the level of knowledge and magnitude of stress experienced by pregnant women during the COVID-19 pandemic. The study found that 55% of respondents had poor knowledge</em><em>,</em><em> and 54% had moderate stress levels. There was no significant relationship between knowledge level and stress level among pregnant women during the COVID-19 pandemic (p = 0.997). It is important to note that having good knowledge does not necessarily guarantee lower stress levels, and vice versa. Health workers should not only provide education about COVID-19 but also examine stress levels in pregnant women.</em></p> <p style="text-align: justify;"><strong><em>Keyword</em></strong><strong><em>s:</em></strong> <em>Covid-19, knowledge level, stress level, pregnant women</em></p> <p style="text-align: justify;">&nbsp;</p> <p style="text-align: justify;"><strong>Abstrak</strong>—Kondisi pandemi Covid-19 menimbulkan beberapa dampak negatif bagi beberapa orang, terutama bagi ibu hamil yang sedang mengalami perubahan fisiologi, hormonal, dan psikologis. Salah satu dampak negatif yang mungkin ditimbulkan yaitu stres. Pengetahuan mengenai Covid-19, efek bagi ibu dan bayi masih relatif sulit didapatkan karena masih sedikit penelitian yang dilakukan. Selain itu, pengetahuan juga merupakan salah satu faktor internal penyebab terjadinya stress. Penelitian ini bertujuan untuk mengetahui tingkat pengetahuan, tingkat stress dan hubungan antara tingkat pengetahuan dan tingkat stress pada ibu hamil pada saat pandemi Covid-19. Penelitian ini merupakan penelitian kuantitatif dengan metode observasional analitik dan desain studi <em>cross sectional. </em>Teknik sampling yang digunakan pada penelitian ini metode <em>Purposive Sampling</em>. Data dikumpulkan dengan membagikan kuesioner yang terdiri dari pernyataan-pernyataan mengenai tingkat pengetahuan dan seberapa besar skala stress ibu hamil pada saat pandemi Covid-19. Hasil penelitian menunjukkan bahwa terdapat 55% responden memiliki pengetahuan yang kurang baik, serta 54% responden memiliki tingkat stress sedang. Tidak didapatkan hubungan yang signifikan antara tingkat pengetahuan dan tingkat stress ibu hamil pada saat pandemi Covid-19 (p=0,997). Tingkat pengetahuan seseorang yang baik tidak menjamin tingkat stress ibu hamil pada saat pandemi Covid-19 menjadi ringan, dan sebaliknya. Diharapkan tenaga kesehatan tidak hanya memberikan edukasi mengenai pengetahuan Covid-19 saja tetapi dapat mengkaji permasalahan stres pada ibu hamil.</p> <p style="text-align: justify;"><strong>Kata kunci:</strong><em> Covid-19, tingkat pengetahuan, tingkat stres, ibu hamil</em></p> Cindy Avia Rizqullah Ananta Yudiarso Yuliana Arisanti Rachmad Poedyo Armanto Copyright (c) 2024 Cindy Avia Rizqullah, Ananta Yudiarso, Yuliana Arisanti , Rachmad Poedyo Armanto (Author) http://creativecommons.org/licenses/by-sa/4.0 2024-03-13 2024-03-13 5 2 69 75 Adakah Hubungan antara Usia dan Gangguan Indera Perasa pada Pasien COVID-19? https://journal.ubaya.ac.id/index.php/kesdok/article/view/5890 <div class="page" title="Page 1"> <div class="section"> <div class="layoutArea"> <div class="column"> <p style="text-align: justify;"><strong><em>Abstract</em></strong><em>—</em><em>COVID-19 (coronavirus disease 2019) is a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The clinical symptoms of COVID-19 patients vary widely, for example the olfactory and taste disorder. Several studies reported the prevalence of taste disorder of 71% to 88.8% in COVID-19 patient. This research aimed to determine the association between age and taste disorders during the spread of the Delta variant of COVID-19. A cross sectional study conducted on 42 subjects. The data was analyzed using Independent T-test. Statistical analyzed showed that 27 out of 42 subjects experienced taste disorders. The mean age of COVID-19 patients with taste disorders was 50 years (SD 12.83). In the independent T-test, a p-value of 0.613 was obtained (p&gt;0.05), which means that there was no association between age and taste disorders. Taste disorders are caused by hyposalivation which begins to occur at the age of 65 and over. This study concluded no significant correlation between age and taste disorders in COVID-19 patients.</em></p> <p style="text-align: justify;"><strong><em>Keywords</em></strong><em>:&nbsp; </em><em>COVID-19 patients, age, taste disorders</em></p> <p style="text-align: justify;"><em>&nbsp;</em></p> <p style="text-align: justify;"><strong>Abstrak</strong>—COVID-19 (<em>coronavirus disease 2019</em>) adalah penyakit pernapasan yang disebabkan oleh <em>Severe Acute Respiratory Syndrome Coronavirus </em>2 (SARS-CoV-2). Gejala klinis pasien COVID-19 sangat bervariasi, di antaranya gangguan indera penghidu dan perasa. Beberapa penelitian melaporkan prevalensi gangguan indera perasa sebesar 71% hingga 88,8% pada pasien COVID-19. Penelitian ini bertujuan untuk mengetahui hubungan rerata usia dengan gangguan indera perasa selama penyebaran COVID-19 varian Delta. Studi <em>cross sectional</em> dilakukan pada 42 subjek penelitian. Teknik pengambilan data adalah total sampling, yaitu pada pasien yang rawat inap karena COVID-19. Data dianalisis dengan menggunakan Uji T-tidak berpasangan. Analisis statistik menunjukkan bahwa 27 dari 42 pasien mengalami gangguan indera perasa. Usia rata-rata pasien COVID-19 dengan gangguan indera perasa adalah 50 tahun (SD 12,83). Pada uji T-tidak berpasangan didapatkan nilai <em>p</em> sebesar 0,613 (<em>p</em>&gt;0,05), yang berarti tidak ada hubungan antara usia dengan gangguan indera perasa.</p> <p style="text-align: justify;"><strong>Kata kunci:</strong> pasien COVID-19, usia, gangguan perasa</p> </div> </div> </div> </div> Khalimatus Suanti Fransiska Fransiska Astrid Pratidina Susilo Copyright (c) 2024 Khalimatus Suanti, Fransiska Fransiska, Astrid Pratidina Susilo (Author) http://creativecommons.org/licenses/by-sa/4.0 2024-06-14 2024-06-14 5 2 76 81 10.24123/kesdok.V5i2.5890 Facial Wash Gel Formulation from Papaya Leaf Extract (Carica papaya L.) With Carbopol 940 As Gelling Agent and Its Stability Study https://journal.ubaya.ac.id/index.php/kesdok/article/view/6082 <p style="text-align: justify;"><em><strong>Abstract</strong>—Propionibacterium acnes is a bacterium that significantly contributes to the development and progression of acne—the phenomenon of bacterial proliferation. The alkaloid carpain present in papaya leaf extract exhibits antibacterial properties against Propionibacterium acnes, a bacterium associated with the development of acne. The facial wash is a cleansing product that removes bacteria and debris from the skin. This study aims to develop a facial wash gel formulation employing papaya leaf extract to treat and inhibit acne-causing bacteria. The formulation will involve the use of different concentrations of Carbopol 940 polymer, namely FI (1%), FII (1.5%), and FIII (2%), as a gelling agent. The research conducted falls under the category of experimental research. The assessment of facial wash gel formulations encompasses various parameters, such as organoleptic evaluation, homogeneity analysis, pH determination, viscosity measurement, spreadability assessment, and foaming capacity examination. The study's findings indicate that the formulation of the FII facial wash gel successfully fulfils all criteria for preparation evaluation. FI fails to satisfy the criteria for spreadability testing, while FIII needs to fulfil the homogeneity and viscosity testing requirements. The viscosity test was significantly affected by different amounts of Carbopol 940, which was used as a gelling agent. The pH, spreadability, and foamability tests were not significantly affected (p&gt;0.05).</em></p> <p style="text-align: justify;"><strong><em>Keyword</em><em>s:</em></strong> <em>acne, carbopol 940, carica papaya, facial wash gel</em></p> <p style="text-align: justify;">&nbsp;</p> <p style="text-align: justify;"><strong>Abstrak</strong>—<em>Propionibacterium acnes</em> merupakan bakteri yang sangat berperan dalam patogenesis timbulnya jerawat. Pertumbuhan bakteri. Di dalam ekstrak daun pepaya terkandung alkaloid karpain yang berfungsi sebagai antibakteri penyebab jerawat (<em>Propionibacterium acnes</em>). Facial wash menjadi salah satu produk yang dapat digunakan untuk membersihkan kulit dari bakteri dan kotoran yang menempel. Penelitian ini bertujuan untuk memformulasikan sediaan facial wash gel dari ekstrak daun pepaya untuk mengobati jerawat serta mencegah pertumbuhan bakteri penyebab jerawat dengan variasi konsentrasi polimer Carbopol 940 sebagai gelling agent yaitu FI (1%), FII (1,5%), dan FIII (2%). Jenis penelitian yang dilakukan adalah penelitian eksperimental. Evaluasi sediaan facial wash gel meliputi pengujian organoleptik, homogenitas, pH, viskositas, daya sebar, dan daya busa. Hasil dari penelitian menunjukkan formulasi sediaan facial wash gel FII memenuhi semua syarat evaluasi sediaan. FI tidak memenuhi syarat uji daya sebar, sedangkan pada FIII tidak memenuhi syarat uji homogenitas dan viskositas. Variasi konsentrasi Carbopol 940 sebagai gelling agent memberikan hasil berpengaruh secara signifikan (p&lt;0,05) terhadap uji viskositas tetapi tidak berpengaruh secara signifikan (p&gt;0,05) terhadap uji pH, daya sebar, dan daya busa.</p> <p style="text-align: justify;"><strong>Kata kunci:</strong><em> daun papaya, gel sabun muka, jerawat, karbopol 940</em></p> <p style="text-align: justify;"><em>&nbsp;</em></p> Tubagus Akmal Yenni Puspita Tanjung Irma Indriani Copyright (c) 2024 Tubagus Akmal, Yenni Puspita Tanjung, Irma Indriani (Author) http://creativecommons.org/licenses/by-sa/4.0 2024-07-01 2024-07-01 5 2 82 88 10.24123/kesdok.V5i2.6082