PROFILE OF ANTIBIOTIC USE AND GERMS MAP ON PNEUMONIA PATIENTS IN THE PULMONARY ROOM Dr. ISKAK HOSPITAL, TULUNGAGUNG
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Keywords:
Pneumonia, Antibiotics, ATC/DDD
Abstract
Pneumonia is an infection of lung tissue caused by bacteria, fungi, viruses or parasites. Antibiotics is a major therapy in pneumonia. The aim of this study was to determine the amount of antibiotic use in DDD / lOO patient-days and to know the profile of germs map in pneumonia patients in Pulmonary Room Dr. Iskak Hospital, Tulungagung period January-June 2Ol7. Observational research method with retrospective data retrieval from patient medical record data and antibiotic usage data from Pharmacy Installation and microbiology culture result data of patient, then analyzed descriptively. The results showed the total amount of antibiotic in l3O unspecified pneumonia patients non ICU inpatient in Pulmonary Room Dr. Iskak Hospital, Tulungagung period January-June 2Ol7 was 5l.28 DDD/lOO patient-days. The most antibiotic types are levofloxacin iv 4O,l4 DDD /lOO patient-days and ceftriaxone 8.7l DDD /lOO patient- days. The profile of the pneumonia-causing germs map can not be determined because there is no data on microbiological culture test results from the patient.
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References
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2. Departemen Kesehatan RI. Pharmaceutical Care Untuk Penyakit Infeksi Saluran Pernapasan. Direktorat Bina Farmasi KOmunitas dan Klinik. Direktur Jenderal Bina Kefarmasian dan Alat Kesehatan. 2005:27-32
3. Ruuskanen O, Lahti E, Jennings LC, Murdoch DR,. Viral pneumonia. Lancet 377 (9773). 2011: 1264–75. doi:10.1016/S0140-6736(10)61459-6. PMID 21435708.
4. Kementerian Kesehatan RI. Riset Kesehatan Dasar 2Ol3. Badan Penelitian Dan Pengembangan Kesehatan. 2013
5. Desrini S. Resistensi Antibiotik Akankah Dapat Dikendalikan?. JKKI.Vol.6,No.4. 2015:i-iii
6. Negara KS. Analisis Implementasi Kebijakan Penggunaan Antibiotika Rasional Untuk Mencegah Resistensi Antibiotika di RSUP Sanglah Denpasar : Studi Kasus Infeksi Methicillin Resistant Staphylococcus Aureus Analysis The Implementation Policy of Rational Use of Antibiotic. Jurnal ARSI. 2014:42-50.
7. Menteri Kesehatan RI. Peraturan Menteri Kesehatan Republik Indonesia Nomor 2406 Tahun 2011 tentang Pedoman Umum Penggunaan Antibiotik. 2011.
8. CDC. Antibiotic / Antimicrobial Resistance CDC. Center for Disease Control and Prevention. 2015: 0-2 http://www.cdc.gov/drugresistance/index.html
9. Siswanto. Kajian Resistensi. In: Seminar Nasional dan Diskusi Interaktif Resistensi Antimikroba. Jakarta: Badan Litbang Kesehatan; 2014: 1-3
10. Yenny, Herwana E. Resistensi dari bakteri enterik: aspek global terhadap antimikroba. Universa Medicina. Vol.26, No.1.2007; 26: 46-56
11. CDC. Core Elements of Hosptal Antibiotic Stewardship Program. 2015. http://www.cdc.gov/getsmart/healthcare/core_element.pdf
12. Menteri Kesehatan RI. Peraturan Menteri Kesehatan Republik Indonesia Nomor 8 Tahun 2015 tentang Program Pengendalian Resistensi Antimikroba di Rumah Sakit. 2015.
13. Pemerintah Kabupaten Tulungagung. Rumah Sakit Umum Daerah Dr.Iskak.
Profil RSUD Dr.Iskak Tulungangung 2Ol6.
14. Meneri Kesehatan RI. Peraturan Menteri Kesehatan Republik Indonesia Nomor 7l Tahun 2Ol3 tentang Pelayanan Kesehatan Pada Jaminan Kesehatan Nasional. 2013.
15. Nugroho F, Utami PI, Yuniastuti I. Evaluasi Penggunaan Antibiotik Pada Penyakit Pnumonia di Rumah Sakit Umum Purbalingga. Jurnal Pharmacy Vol.08. No.01. 2011: 141-153
16. Zhukova OV, Ruina OV, Kononova SV, Konyshkina TM. Analysis of the efficiency of antimicrobial treatment for community-acquired pneumonia clinical practice. Theraperticheskii Arkhiv.2017, 89(8):17-21. doi: 10.17116/terarkh201789817-
17. Li HK, Agweyu A, English M, Bejon P. An Unsupported Preference for Intravenous Antibiotiks. PLoS Med. 2015;12(5):1–7. doi:10.1371/journal.pmed.1001825
18. Misnadiarly. Penyakit Infeksi Saluran Napas, Pneumonia pada Anak, Orang Dewasa, Usia Lanjut Edisi I. Jakarta: pustaka Obor Populer. 2008
19. Cyriac JM, James E. Switch over from intravenous to oral therapy: A concise overview. J Pharmacol Pharmacother. 2014. doi:10.4103/0976-500X.130042.
20. Li HK, Agweyu A, English M, Bejon P. An Unsupported Preference for Intravenous Antibiotiks. PLoS Med. 2015;12(5):1–7. doi:10.1371/journal.pmed.1001825.
21. Kamal AM. Evaluasi Penggunaan Antibiotik Pada Pasien Pneumonia Di RSUD Sukoharjo Tahun 2Ol4 : 1-3
22. Langtri HD, Lamb HM. Levofloxacin, Its Use Infections of the Respiratory
Tract, Skin, Soft Tissues and Urinary Tract. 1999. Pubmed.
23. IDSA. Infectious Diseases Sociaty of America/American Thoracic Society Consensus Guidelines on the Managemen of Community-Acquired Pneumonia in Adults. CID 2007:44 (Suppl 2) S28-S38
24. Brunton L.Parker K, Blumenthal D BI. . Goodman & Gilman’n Manual of Pharmacology and Therapeutics.International. New York: McGraw-Hill; 2008.
25. Wunderink RG, Mandell L. Adjuctive Therapy in Community-Acquired Pneumonia. Semin Respir Crit Med, Chicago. 2012: 311-318
26. Alifia N. Evaluasi Penggunaan Antibiotik Pada Pasien Pneumonia Komunitas Rawat Inap di Rumkital Dr. Mintohardjo Jakarta Tahun 2015.
Published
2018-03-01
Section
Bidang Magister Farmasi Klinis (MFK)
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