PROFIL PEMBERIAN BETA-BLOCKER TERHADAP CARDIOVASCULAR EVENT PADA PASIEN JANTUNG KORONER
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Abstract
Penyakit jantung koroner (PJK) adalah penyakit yang terjadi akibat manifestasi dari penurunan suplai oksigen ke otot jantung karena terjadinya penyempitan aliran darah pada arteri koroner. Selain itu, penyakit jantung koroner juga membawa arti penyakit kompleks yang disebabkan oleh menurunnya atau terhambatnya aliran darah pada satu atau lebih arteri yang mensuplai darah ke jantung. Salah satu terapi obat pada penatalaksanaan penyakit jantung koroner adalah beta-blocker. Beta-blocker bekerja dengan cara memblok reseptor β‐adrenoseptor. Beta-blocker digunakan untuk mencegah terjadinya nyeri dada dan mencegah Cardiovascular Event jangka panjang. Beta-blocker efektif dalam pengobatan angina sebagai monoterapi atau bisa dikombinasikan dengan nitrat dan atau calcium channel blockers. Saat ini, pengobatan dengan β-blocker masih dianggap pengobatan standart untuk pasien dengan Coronary Artery Disease, terutama pada pasien yang memiliki infark miokard. Berdasarkan data yang diperoleh, sebanyak 35 pasien mengalami nyeri dada dari 63 pasien yang menggunakan beta-blocker dan 37 pasien mengalami nyeri dada dari 55 pasien yang tidak menggunakan beta-blocker. Dari analisa statistik dengan uji Mann-Whitney yang diperoleh, nilai P= 0,195 > 0,05 hal tersebut menyatakan bahwa antara kedua kelompok tersebut baik yang menggunakan beta-blocker dan yang tidak menggunakan beta-blocker tidak terdapat perbedaan yang signifikan terhadap cardiovascular event.
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References
ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease Vol. 60, No. 24, 2012 ISSN 0735-1097/$36.00 © 2012 by the American College of Cardiology Foundation and the American Heart Association, Inc.
ACC/AHA Guideline for The Mnagement of Heart Failure, © 2012 by the American College of Cardiology Foundation and the American Heart Association, Inc.
AHA/ACC Guideline on Lifestyle Management to Reduce Cardiovascular Risk: A Report Guidelines of the American College of Cardiology/American Heart Association Task Force on Practice, published online November 12, 2013; Print ISSN: 0009-7322. Online ISSN: 1524-4539 © 2013 American Heart Association, Inc.
American College of Cardiology Foundation and the American Heart Association, 2014, ACC/AHA 2002 Guideline Update for the Management of Patients With Chronic Stable Angina.
American Diabetes Association, Standards of Medical Care in Diabetes- 2013. Diabetes Care 2013, 36(S1):S11-66.
Australian Health Survey: First Results, 2011-12. ABS cat. no. 4364.0.55.001. Canberra:ABS.
Badan Penelitian Dan Pengembangan Kesehatan Kementerian Kesehatan RI, 2013, Riset Kesehatan Dasar, Jakarta: KementerianKesehatan, ix-91.
Bangalore S, Steg G, Deedwania P et al, 2012, Blocker Use and Clinical Outcomes in Stable Outpatients With and Without Coronary Artery Disease, JAMA. 2006;295(2):180-189, E1-E8.
Beddhu S, Bruns FJ, Saul M, Seddon P, Zeidel ML, 2000, A Simple Comorbidity Scale Predicts Clinical Outcomes and Costs in Dialysis Patient, The American Journal of Medicine. 108:609-613.
Canadian Cardiovascular Society, 2013, 2012 Update of The Canadian Cardiovascular Society Guidelines for The Diagnosis and Treatment of Dyslipidemia for The Prevention of Cardiovascular Disease In The Adult, 151-167.
Cruikhshank J.M & Prichard B.N.C, 1987, Hypertension, Beta Blockers in Clinical Practice, Churchill Livingstone, New York.
Dickinson, John. C,. Strokes and their relationship. London : Lippincot Williams and Wilkins, 2009.
European Society Cardiology, 2013, 2013 ESC guidelines on the management of stable coronary artery disease, European Heart Journal, 10.
European Society of Cardiology, 2006, Guidelines on the management of stableangina pectoris: full text, European Heart Journal, 2-22.
European Society of Cardiology, 2013, 2013 ESC Guidelines for the management of stable coronary artery disease - addenda, European Heart Journal, 2-3.
Jhusuf I.H.A, et al, 2011, British National Formulary, 67th edition, London, GGP Media GmbH.
Fitchett D, Goodman S, Langer A, 2001, New Advances in the Management of Acute Coronary Syndromes: Matching Treatment to Risk. CMAJ 2001; 164 (9).
Hidayat AA, 2010, Metode Penelitian Kesehatan Paradigma Kualitatif, Health Books Publishing, Surabaya, 3-220
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