Faktor yang Mempengaruhi Keterlambatan Pra-Rumah Sakit pada Pasien ST Elevation Myocardial Infarction (STEMI) : Kajian Literatur
DOI:
Abstract Views:
826 times
PDF Downloads:
913 times
Abstract
Abstract—ST-elevation myocardial infarction (STEMI) is a lethal condition. Treatment modality and success mostly depend on time since onset of symptoms. In STEMI, prehospital delay is a significant factor, decreasing likelihood of revascularization and increasing mortality.A greater understanding of the contributing factors may help to reduce delays. This review aimed to map factors associated with prehospital delay in patients with STEMI. We identified patient and transport factors predicting prehospital delay. This review may help the national health management system to identify the factors associated with prehospital delay and it will help in planning interventions to reduce patient delays and to improve the outcome and reduces morbidity and mortality of patients with STEMI.
Keywords: acute myocardial infarction; prehospital delay; risk factors; stemi
Abstrak—ST-elevation mycardial infarction (STEMI) merupakah salah satu penyakit yang mematikan. Keberhasilan pengobatan sebagian besar bergantung pada waktu sejak timbulnya gejala. Pada kasus STEMI, keterlambatan pra-rumah sakit merupakan faktor yang signifikan menurunkan kemungkinan revaskularisasi dan meningkatkan mortalitas pasien. Pemahaman yang baik tentang faktor-faktor yang berkontribusi terhadap keterlambatan pra-rumah sakit dapat menjadi suatu masukan bagi intervensi untuk mengurangi waktu keterlambatan. Kajian ini bertujuan untuk memetakan faktor yang terkait dengan keterlambatan pra-rumah sakit pada pasien STEMI. Kami mengidentifikasi faktor pasien dan faktor transportasi yang memprediksi keterlambatan pra-rumah sakit. Hasil kajian ini dapat membantu sistem manajemen kesehatan nasional untuk mengidentifikasi faktor-faktor yang terkait dengan keterlambatan pra-rumah sakit dan ini akan membantu dalam merencanakan intervensi untuk mengurangi keterlambatan pasien dan untuk meningkatkan prognosis serta mengurangi morbiditas dan mortalitas pasien STEMI.
Kata kunci: infark miokard akut; keterlambatan pra-rumah sakit; faktor risiko; stemi
Downloads
References
World Health Organization. Global Health Estimates 2020 : Death by Cause, Age, Sex, by Country and by Region, 2000-2019 2020.
Martini F, Hautekeete N, Van Dijk H, Touzet P, Biancardi E. Fundamentals of Anatomy & Physiology 11 edition. 2019. https://doi.org/10.1007/978-3-030-28748-1_4.
Kemenkes. Kementerian Kesehatan Republik Indonesia. Kementeri Kesehat RI 2019;1:1.
Kemenkes RI. Profil Kesehatan Indo-nesia. 2016.
PERKI PDSKI. Pedoman Tata Laksana Sindrom Koroner Akut. Indones Hear Assoc 2018. https://doi.org/10.5694/j.1326-5377.2007.tb01292.x.
Santos-Gallego CG, Picatoste B, Badimón JJ. Pathophysiology of acute coronary syndrome. Curr Atheroscler Rep 2014;16. https://doi.org/10.1007/s11883-014-0401-9.
Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J 2018;39:119–77. https://doi.org/10.1093/eurheartj/ehx393.
Scholz KH, Maier SKG, Maier LS, Lengenfelder B, Jacobshagen C, Jung J, et al. Impact of treatment delay on mortality in ST-segment elevation myocardial infarction (STEMI) patients presenting with and without haemodynamic instability: Results from the German prospective, multicentre FITT-STEMI trial. Eur Heart J 2018;39:1065–74. https://doi.org/10.1093/eurheartj/ehy004.
Dharma S, Juzar DA, Firdaus I, Soerianata S, Wardeh AJ, Jukema JW. Acute myocardial infarction system of care in the third world. Netherlands Hear J 2012;20:254–9. https://doi.org/10.1007/s12471-012-0259-9.
Goldberg RJ, Glatfelter K, Burbank-Schmidt E, Lessard D, Gore JM. Trends in community mortality due to coronary heart disease. Am Heart J 2006;151:501–7. https://doi.org/10.1016/j.ahj.2005.04.024.
Sanchis-Gomar F, Perez-Quilis C, Leischik R, Lucia A. Epidemiology of coronary heart disease and acute coronary syndrome. Ann Transl Med 2016;4:1–12. https://doi.org/10.21037/atm.2016.06.33.
Menees DS, Peterson ED, Wang Y, Curtis JP, Messenger JC, Rumsfeld JS, et al. Door-to-Balloon Time and Mortality among Patients Undergoing Primary PCI. N Engl J Med 2013;369:901–9. https://doi.org/10.1056/nejmoa1208200.
Kharbach A, Obtel M, Baba MA, Lahlou L, Razin R. Pre-Hospital Delay and Associated Factors of Ischemic Stroke in Northern Mediterranean Countries: A Literature Review. Eur J Basic Med Sci 2021;9:5–16. https://doi.org/10.21601/ejbms/10817.
Khaled MFI, Banerjee SK, Adhikary DK, Chowdhury MT, Mahmood M, Rahman MM, et al. Factors Influencing Pre-Hospital Delay In Patients with Acute Myocardial Infarction. Univ Hear J 2019;15:79–85. https://doi.org/10.3329/uhj.v15i2.42666.
Ren L, Ye H, Wang P, Cui Y, Cao S, Lv S. Comparison of long-term mortality of acute ST-segment elevation myocardial infarction and non-ST-segment elevation acute coronary syndrome patients after percutaneous coronary intervention. Int J Clin Exp Med 2014;7:5588–92.
Bouisset F, Ruidavets JB, Dallongeville J, Moitry M, Montaye M, Biasch K, et al. Comparison of short-and long-term prognosis between ST-Elevation and non-ST-Elevation myocardial infarction. J Clin Med 2021;10:1–10. https://doi.org/10.3390/jcm10020180.
Youssef GS, Kassem HH, Ameen OA, Al Taaban HS, Rizk HH. Pre-hospital and hospital delay in patients with non-ST elevation acute coronary syndromes in tertiary care. Egypt Hear J 2017;69:177–81. https://doi.org/10.1016/j.ehj.2017.01.002.
Albarqouni L, Smenes K, Meinertz T, Schunkert H, Fang X, Ronel J, et al. Patients’ knowledge about symptoms and adequate behaviour during acute myocardial infarction and its impact on delay time: Findings from the multicentre MEDEA Study. Patient Educ Couns 2016;99:1845–51. https://doi.org/10.1016/j.pec.2016.06.007.
Poorhosseini H, Saadat M, Salarifar M, Mortazavi SH, Geraiely B. Pre-Hospital Delay and Its Contributing Factors in Patients with ST-Elevation Myocardial Infarction; a Cross sectional Study. Arch Acad Emerg Med 2019;7:e29. https://doi.org/10.22037/aaem.v7i1.349.
Shen C, Li C, Wang J, Yin J, Lou P, Wang Z, et al. In-depth look into urban and rural disparities in prehospital delay in patients with acute ST-elevation myocardial infarction and its impact on prognosis: a prospective observational study. BMJ Open 2022;12:1–7. https://doi.org/10.1136/bmjopen-2022-063795.
Feng L, Li M, Xie W, Zhang A, Lei L, Li X, et al. Prehospital and in-hospital delays to care and associated factors in patients with STEMI: An observational study in 101 non-PCI hospitals in China. BMJ Open 2019;9:1–8. https://doi.org/10.1136/bmjopen-2019-031918.
Albrahim M, Ahmed AM, Alwakeel A, Hijji F, Al-Mallah MH. Predictors of delayed pre-hospital presentation among patients with ST-segment elevation myocardial infarction. Qatar Med J 2016;2016:1–5. https://doi.org/10.5339/qmj.2016.7.
Kim HS, Lee KS, Eun SJ, Choi SW, Kim DH, Park TH, et al. Gender differences in factors related to prehospital delay in patients with ST-segment elevation myocardial infarction. Yonsei Med J 2017;58:710–9. https://doi.org/10.3349/ymj.2017.58.4.710.
Eka Harsanti, Septiana; Dwi sulistyawati, s; Subekti Wulandari I. Pengalaman Keluarga Dalam Menghadapi Kejadian Serangan Akut Miokard Infark (AMI) pada Anggota Keluarga di RSUD Sragen 2015;51:1–10.
George L, Ramamoorthy L, Satheesh S, Saya RP, Subrahmanyam DKS. Prehospital delay and time to reperfusion therapy in ST elevation myocardial infarction. J Emergencies, Trauma Shock 2017;10:64–9. https://doi.org/10.4103/0974-2700.201580.
Lim SC, Rahman A, Yaacob NM. Pre-hospital factors influencing time of arrival at emergency departments for patients with acute ST-elevation myocardial infarction. Malaysian J Med Sci 2019;26:87–98. https://doi.org/10.21315/mjms2019.26.1.8.
Mujtaba SF, Sohail H, Ram J, Waqas M, Hassan M, Sial JA, et al. Pre-hospital Delay and Its Reasons in Patients With Acute Myocardial Infarction Presenting to a Primary Percutaneous Coronary Intervention-Capable Center. Cureus 2021. https://doi.org/10.7759/cureus.12964.
Stehli J, Dinh D, Dagan M, Duffy SJ, Brennan A, Smith K, et al. Sex differences in prehospital delays in patients with st-segment-elevation myocardial infarction undergoing percutaneous coronary intervention. J Am Heart Assoc 2021;10:1–12. https://doi.org/10.1161/JAHA.120.019938.
Caltabellotta T, Magne J, Salerno B, Pradel V, Petitcolin PB, Auzemery G, et al. Characteristics associated with patient delay during the management of ST-segment elevated myocardial infarction, and the influence of awareness campaigns. Arch Cardiovasc Dis 2021;114:305–15. https://doi.org/10.1016/j.acvd.2020.09.004.
Hu DQ, Hao YC, Liu J, Yang N, Yang YQ, Sun ZQ, et al. Pre-hospital delay in patients with acute myocardial infarction in China: findings from the Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome (CCC-ACS) project. J Geriatr Cardiol 2022;19:276–83. https://doi.org/10.11909/j.issn.1671-5411.2022.04.005.
Pereira H, Calé R, Pinto FJ, Pereira E, Caldeira D, Mello S, et al. Factors influencing patient delay before primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: The Stent for life initiative in Portugal. Rev Port Cardiol (English Ed 2018;37:409–21. https://doi.org/10.1016/j.repce.2017.07.009.
Jäger B, Haller PM, Piackova E, Kaff A, Christ G, Schreiber W, et al. Predictors of transportation delay in patients with suspected ST-elevation-myocardial infarction in the VIENNA-STEMI network. Clin Res Cardiol 2020;109:393–9. https://doi.org/10.1007/s00392-019-01520-z.
Nguyen HL, Gore JM, Saczynski JS, Yarzebski J, Reed G, Spencer FA, et al. Age and sex differences and 20-year trends (1986 to 2005) in prehospital delay in patients hospitalized with acute myocardial infarction. Circ Cardiovasc Qual Outcomes 2010;3:590–8. https://doi.org/10.1161/CIRCOUTCOMES.110.957878.
Lawesson SS, Isaksson RM, Ericsson M, Ängerud K, Thylén I. Gender disparities in first medical contact and delay in ST-elevation myocardial infarction: A prospective multicentre Swedish survey study. BMJ Open 2018;8:1–10. https://doi.org/10.1136/bmjopen-2017-020211.
Khaled MFI, Adhikary DK, Islam MM, Alam MM, Rahman MW, Chowdhury MSIT, et al. Factors Responsible for Prehospital Delay in Patients with Acute Coronary Syndrome in Bangladesh. Med 2022;58:1–11. https://doi.org/10.3390/medicina58091206.
Mohan B, Bansal R, Dogra N, Sharma S, Chopra A, Varma S, et al. Factors influencing prehospital delay in patients presenting with ST-elevation myocardial infarction and the impact of prehospital electrocardiogram. Indian Heart J 2018;70:S194–8. https://doi.org/10.1016/j.ihj.2018.10.395.
Smolderen KG, Spertus JA, Nallamothu BK, Krumholz HM, Tang F, Ross JS, et al. Health care insurance, financial concerns in accessing care, and delays to hospital presentation in acute myocardial infarction. Jama 2010;303:1392–400. https://doi.org/10.1001/jama.2010.409.
Rosjidi CH. Kesalahan Perawatan Di Rumah Dan Dampak Keterlambatan Di Rujuk Di Rumah Sakit Pada Pasien Penyakit Jantung Koroner. J Keperawatan 2020;11:1–9.
Wang X, Hsu LL. Treatment-seeking delays in patients with acute myocardial infarction and use of the emergency medical service. J Int Med Res 2013;41:231–8. https://doi.org/10.1177/0300060512474567.
Nilsson G, Mooe T, Söderström L, Samuelsson E. Pre-hospital delay in patients with first time myocardial infarction: An observational study in a northern Swedish population. BMC Cardiovasc Disord 2016;16:1–10. https://doi.org/10.1186/s12872-016-0271-x.
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
- Articles published in Keluwih: JKK are licensed under a Creative Commons Attribution-ShareAlike 4.0 International license. You are free to copy, transform, or redistribute articles for any lawful purpose in any medium, provided you give appropriate credit to the original author(s) and the journal, link to the license, indicate if changes were made, and redistribute any derivative work under the same license.
- Copyright on articles is retained by the respective author(s), without restrictions. A non-exclusive license is granted to Kluwih: JKK to publish the article and identify itself as its original publisher, along with the commercial right to include the article in a hardcopy issue for sale to libraries and individuals.
- By publishing in Keluwih: JKK, authors grant any third party the right to use their article to the extent provided by the Creative Commons Attribution-ShareAlike 4.0 International license.
